Arsenal v Chelsea. Premier League fixtures.

Arsenal face Chelsea at Emirates as Arsene Wenger will try to beat Jose Mourinho for the first time in career.

Arsenal v Chelsea

The Gunners have not won in the last three matches and were brushed at Etihad last week. If they lose the derby they will drop from the top spot. However, Wenger will have to make changes in the squad as Jack Wilshere will serve suspension for an offensive gesture during the match against Manchester City and Laurent Koscielny will be unavailable with a knee inury.

In midweek Chelsea were knocked out from the League Cup by Sunderland in dramatic fashion and will be looking for revenge on Monday. The Blues have won eight out of eleven last matches against Arsenal. Michael Essien is unavailable through suspension.

Southampton v Tottenham Hotspur

The Saints who had an impressive start of the season have now not won since 9 November and have dropped to the ninth position behind their Sunday opponents. Tottenham are still uncertain of their next manager and Tim Sherwood will be in charge of the team once again after he lost his first match at the helm to West Ham United in Capital One Cup on Wednesday. Christian Eriksen returned to full fitness and will be available for the game. Sandro, Andros Townsend and Jan Vertonghen will be missing with injuries and Paulinho will be absent due to suspension. Nathaniel Clyne, Victor Wanyama and Artur Boruc are the main setbacks for Mauricio Pochettino.

Manchester United v West Ham United

United have lost their last two Premier League matches at Old Trafford and must improve to beat the Hammers, who will travel to Manchester inspired after shocking Tottenham in the League Cup. David Moyes will be having a headache picking the forward line as Wayne Rooney’s recent groin injury forced him to miss the Stoke match on Wednesday and Robin van Persie is a long-term absentee. Ricardo Vaz Te, Stewart Downing and Winston Reid are all unavailable for Sam Allardyce, while Kevin Nolan will be serving a ban.

Liverpool v Cardiff City
Crystal Palace v Newcastle United
Fulham v Manchester City
Manchester United v West Ham United
Stoke City v Aston Villa
Sunderland v Norwich City
West Bromwich Albion v Hull City
Southampton v Tottenham Hotspur
Swansea City v Everton
Arsenal v Chelsea